PHARMACOGNOSTIC AND BIOLOGICAL STUDIES OF Artemisia absinthium L. LEAF / (Kayıt no. 291591)
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| 000 -BAŞLIK | |
|---|---|
| Sabit Uzunluktaki Kontrol Alanı | 03764nam a22003017a 4500 |
| 003 - KONTROL NUMARASI KİMLİĞİ | |
| Kontrol Alanı | KOHA |
| 005 - EN SON İŞLEM TARİHİ ve ZAMANI | |
| Kontrol Alanı | 20231030140940.0 |
| 008 - SABİT UZUNLUKTAKİ VERİ ÖGELERİ - GENEL BİLGİ | |
| Sabit Alan | 231030d2023 cy ||||| m||| 00| 0 eng d |
| 040 ## - KATALOGLAMA KAYNAĞI | |
| Özgün Kataloglama Kurumu | CY-NiCIU |
| Kataloglama Dili | eng |
| Çeviri Kurumu | CY-NiCIU |
| Açıklama Kuralları | rda |
| 041 ## - DİL KODU | |
| Metin ya da ses kaydının dil kodu | eng |
| 090 ## - Yerel Tasnif No | |
| tasnif no | YL 3148 |
| Cutter no | K25 2023 |
| 100 1# - KİŞİ ADI | |
| Yazar Adı (Kişi adı) | Kakkaba, Amina Abubakar |
| 245 10 - ESER ADI BİLDİRİMİ | |
| Başlık | PHARMACOGNOSTIC AND BIOLOGICAL STUDIES OF Artemisia absinthium L. LEAF / |
| Sorumluluk Bildirimi | AMINA ABUBAKAR KAKKABA; SUPERVISOR: ASST. PROF. DR. EMMANUEL MSHELIA HALILU |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2023 |
| 300 ## - FİZİKSEL TANIMLAMA | |
| Sayfa, Cilt vb. | xii, 71 sheets; |
| Boyutları | 31 cm. |
| Birlikteki Materyal | 1 CD-ROM |
| 336 ## - CONTENT TYPE | |
| Source | rdacontent |
| Content type term | text |
| Content type code | txt |
| 337 ## - MEDIA TYPE | |
| Source | rdamedia |
| Media type term | unmediated |
| Media type code | n |
| 338 ## - CARRIER TYPE | |
| Source | rdacarrier |
| Carrier type term | volume |
| Carrier type code | nc |
| 502 ## - TEZ NOTU | |
| Tez Notu | Thesis (MSc) - Cyprus International University. Institute of Graduate Studies and Research Pharmacognosy Department |
| 504 ## - BİBLİYOGRAFİ NOTU | |
| Bibliyografi Notu | Includes bibliography (sheets 58-71) |
| 520 ## - ÖZET NOTU | |
| Özet notu | ABSTRACT <br/>Artemisia absinthium L. (Wormwood) is a plant which belongs to the family <br/>Asteraceae and it has been used by traditional healers to treat many ailments and <br/>infections in African traditional medicine. It is popularly used in pharmaceutics to <br/>manufacture artemisinin-based combination therapy against malaria. There is a <br/>growing concern about the scourge of diseases caused by excessive free radicals in the <br/>body and lack of standardization of medicinal herbal products. Therefore, this research <br/>is aimed at evaluating the antibacterial and antioxidant activities of the extract. The <br/>powdered leaf powder was evaluated for its pharmacognostic profiles and then <br/>extracted successively using maceration method with methanol as solvent. AgNPs was <br/>characterized with the following techniques such as UV/VIS and FTIR. The extracts <br/>were screened for their phytochemical constituents using standard protocols. The <br/>preliminary phytochemical screening of the extracts revealed the presence of tannins, <br/>saponins, flavonoids and steroids and terpenoids. The thin layer chromatography <br/>(TLC) profiles of the resulting extracts were determined using suitable solvent <br/>systems. The petroleum ether extract showed 3 spots and the Rf values are 0.78, 0.44 <br/>and 0.14, whereas 8 spots were found in methanol extract with Rf values 0.90, 0.77, <br/>0.58, 0.35, 0.29, 0.19, 0.12 and 0.08. The antioxidant (free radical scavenging) activity <br/>of the extracts was measured using DPPH (2, 2-diphenyl-1- picryl hydrazyl) with <br/>ascorbic acid used as standard. The IC50 of the ascorbic acid and the extract were <br/>1.305mg/ml and 0.4128mg/ml respectively. The results were expressed in terms of <br/>percentage inhibition. The free radical scavenging activity of the extracts revealed <br/>lower activity and a subsequent increase then decline with decrease in concentration <br/>in the methanol extract when DPPH was used. The zone of inhibition for the extract, <br/>nanoparticles aare 0mm, 0.67mm and 9.33 for E. coli and 3.33mm, 1.67mm and <br/>12.33mm for Bacillus subtillis respectively. The minimum inhibitory concentration <br/>(MIC) of extract, nanoparticles and standard antibiotic are 0.44µg/ml, 0.40µg/ml and <br/>0.24µg/ml respectively. The results indicated that the extracts contain secondary <br/>metabolites which may be responsible for the antioxidant and antimicrobial activity <br/>demonstrated by the extract of A. absinthium L. and silver nanoparticles (AgNPs).<br/>Keywords: Antimicrobial characteristics, Antioxidant characteristics, Artemisia <br/>absinthium, Pharmacognostic characteristics.<br/> |
| 650 #0 - KONU BAŞLIĞI EK GİRİŞ - KONU TERİMİ | |
| Konusal terim veya coğrafi ad | Anti-infective agents |
| Alt başlık biçimi | Dissertations, Academic |
| 650 #0 - KONU BAŞLIĞI EK GİRİŞ - KONU TERİMİ | |
| Konusal terim veya coğrafi ad | Antioxidants |
| Alt başlık biçimi | Dissertations, Academic |
| 650 #0 - KONU BAŞLIĞI EK GİRİŞ - KONU TERİMİ | |
| Konusal terim veya coğrafi ad | Absinth wormwood |
| Alt başlık biçimi | Dissertations, Academic |
| 650 #0 - KONU BAŞLIĞI EK GİRİŞ - KONU TERİMİ | |
| Konusal terim veya coğrafi ad | Pharmacognosy |
| Alt başlık biçimi | Dissertations, Academic |
| 700 1# - EK GİRİŞ - KİŞİ ADI | |
| Yazar Adı (Kişi adı) | Halilu, Emmanuel Mshelia |
| İlişkili Terim | supervisor |
| 942 ## - EK GİRİŞ ÖGELERİ (KOHA) | |
| Sınıflama Kaynağı | Dewey Onlu Sınıflama Sistemi |
| Materyal Türü | Thesis |
| Geri Çekilme Durumu | Kayıp Durumu | Sınıflandırma Kaynağı | Kredi için değil | Koleksiyon Kodu | Kalıcı Konum | Mevcut Konum | Raf Yeri | Kayıt Tarih | Source of acquisition | Yer Numarası | Demirbaş Numarası | Son Görülme Tarihi | Fatura Tarihi | Materyal Türü | Genel / Bağış Notu | Toplam Ödünçverme |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Onlu Sınıflama Sistemi | Tez Koleksiyonu | CIU LIBRARY | CIU LIBRARY | Tez Koleksiyonu | 30.10.2023 | Bağış | YL 3148 K25 2023 | T3529 | 30.10.2023 | 30.10.2023 | Thesis | Pharmacognosy Department | ||||
| Dewey Onlu Sınıflama Sistemi | CIU LIBRARY | CIU LIBRARY | Görsel İşitsel | 30.10.2023 | Bağış | YL 3148 K25 2023 | CDT3529 | 30.10.2023 | 30.10.2023 | Suppl. CD | Pharmacognosy Department |