MARC ayrıntıları
| 000 -BAŞLIK |
|---|
| Sabit Uzunluktaki Kontrol Alanı |
03375nam a22002897a 4500 |
| 003 - KONTROL NUMARASI KİMLİĞİ |
|---|
| Kontrol Alanı |
KOHA |
| 005 - EN SON İŞLEM TARİHİ ve ZAMANI |
|---|
| Kontrol Alanı |
20231106110526.0 |
| 008 - SABİT UZUNLUKTAKİ VERİ ÖGELERİ - GENEL BİLGİ |
|---|
| Sabit Alan |
231106d2023 cy ||||| m||| 00| 0 eng d |
| 040 ## - KATALOGLAMA KAYNAĞI |
|---|
| Özgün Kataloglama Kurumu |
CY-NiCIU |
| Kataloglama Dili |
eng |
| Çeviri Kurumu |
CY-NiCIU |
| Açıklama Kuralları |
rda |
| 041 ## - DİL KODU |
|---|
| Metin ya da ses kaydının dil kodu |
eng |
| 090 ## - Yerel Tasnif No |
|---|
| tasnif no |
YL 3104 |
| Cutter no |
C44 2023 |
| 100 1# - KİŞİ ADI |
|---|
| Yazar Adı (Kişi adı) |
Ceesay, İsmaila |
| 245 10 - ESER ADI BİLDİRİMİ |
|---|
| Başlık |
GREEN SYNTHESIS OF ZINC OXIDE NANOPARTICLES USING ETHANOLIC LEAF EXTRACT OF OLEA EUROPAEA L. AND IT’S IN VITRO EVALUATION ON MDA-MB 231 CANCER CELLS LINES, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIY / |
| Sorumluluk Bildirimi |
ISMAILA CEESAY SUPERVISOR ASST. PROF. DR. PWADUBASHIYI COSTON PWAVO DI |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Date of production, publication, distribution, manufacture, or copyright notice |
2023 |
| 300 ## - FİZİKSEL TANIMLAMA |
|---|
| Sayfa, Cilt vb. |
xv, 106 sheets; |
| Boyutları |
31 cm. |
| Birlikteki Materyal |
1 CD-ROM |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| Content type code |
txt |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| Media type code |
n |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type term |
volume |
| Carrier type code |
nc |
| 502 ## - TEZ NOTU |
|---|
| Tez Notu |
Thesis (MSc) - Cyprus International University. Institute of Graduate Studies and Research Bioengineering Department |
| 504 ## - BİBLİYOGRAFİ NOTU |
|---|
| Bibliyografi Notu |
Includes bibliography (sheets 96-106) |
| 520 ## - ÖZET NOTU |
|---|
| Özet notu |
ABSTRACT<br/>Most women get breast cancer, 1.4 million cases are diagnosed annually worldwide. <br/>Zinc oxide nanoparticle biosynthesis of olive leaves is a popular traditional leave<br/>study. This study was aim to synthesised and characterised zinc oxide nanoparticles <br/>using Olea europaea L to test their cytotoxic impact on breast cancer cell lines MDAMB 231, antioxidant, and antibacterial properties on gram-negative and gram-positive <br/>bacteria. The GC-MS analysis shows that there are some bioactive compound presents<br/>in Olea europaea L and the UV spectra analysis indicated the spectrum with the peaks <br/>of 313, 285, 257, 227 and 201 nm with absorption respectively. The zeta size has <br/>shown a size of 86.14 nm with a charge of -12.64 mV X-RAY Diffraction (XRD) <br/>and the Fourier Transform Infrared Spectrophotometer (FTIR) has been used. The <br/>antioxidant result shows an antioxidant activity of the ZnO NPs and Zn against the free <br/>radicals while higher activity was recorded in Olea europaea L. The ZnO NPs, Zn and <br/>Olea europaea L against the six bacterial has shown a zone of inhibition for the <br/>following bacterial P. aeruginosa 29, E. coli 12, S. aureus 16, B. cereus 8, while the <br/>two bacterial E faecalis 0, Legionella pneumophila 0, has not indicated any zone of <br/>inhibition which has been found by other researcher of similar result E Faecalis, <br/>legionella pnenumophila. DMEM-grown MDA MB 231 cells for positive control were <br/>100% viable. After 24 hours of treatment, cell was reduced to 80%. The higher dose<br/>reduced cells from 100% to 80% and after 48-hour of incubation there was 68% of <br/>effects of ZnO NPs. Positive control of MDA MB 231 and DMEM as a media shown<br/>100% viability in 24-hour at the beginning, Minor influence seen in 24-hour cell death <br/>of 80%, while the positive control still maintains the cell viability at 100%. ZnO <br/>nanoparticles activity caused shrank, aggregated, deformed, adhered, and proliferated <br/>slower MDA MB 231 breast cancer cells as evident of Apoptosis and shrinkage <br/>indicate cell death. <br/>Keywords: Antibacterial, Anticancer Antioxidant, Breast Cancer and Olea europaea<br/>L |
| 650 #0 - KONU BAŞLIĞI EK GİRİŞ - KONU TERİMİ |
|---|
| Konusal terim veya coğrafi ad |
Antibacterial agents |
| Alt başlık biçimi |
Dissertations, Academic |
| 650 #0 - KONU BAŞLIĞI EK GİRİŞ - KONU TERİMİ |
|---|
| Konusal terim veya coğrafi ad |
Breast |
| Alt başlık biçimi |
Dissertations, Academic |
| Genel Alt Konu |
Cancer |
| 700 1# - EK GİRİŞ - KİŞİ ADI |
|---|
| Yazar Adı (Kişi adı) |
Pwavodi, Pwadubashiyi Coston |
| İlişkili Terim |
supervisor |
| 942 ## - EK GİRİŞ ÖGELERİ (KOHA) |
|---|
| Sınıflama Kaynağı |
Dewey Onlu Sınıflama Sistemi |
| Materyal Türü |
Thesis |