THE POTENTIAL WOUND HEALING ACTIVITY OF CHITOSAN-GUM ARABIC COMPLEX LOADED WITH CHAMOMILE AND HONEY / (Kayıt no. 292959)
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| 000 -BAŞLIK | |
|---|---|
| Sabit Uzunluktaki Kontrol Alanı | 02997nam a22002657a 4500 |
| 003 - KONTROL NUMARASI KİMLİĞİ | |
| Kontrol Alanı | KOHA |
| 005 - EN SON İŞLEM TARİHİ ve ZAMANI | |
| Kontrol Alanı | 20250109100018.0 |
| 008 - SABİT UZUNLUKTAKİ VERİ ÖGELERİ - GENEL BİLGİ | |
| Sabit Alan | 240927d2024 cy eo||| |||| 00| 0 eng d |
| 040 ## - KATALOGLAMA KAYNAĞI | |
| Özgün Kataloglama Kurumu | CY-NiCIU |
| Kataloglama Dili | eng |
| Çeviri Kurumu | CY-NiCIU |
| Açıklama Kuralları | rda |
| 041 ## - DİL KODU | |
| Metin ya da ses kaydının dil kodu | eng |
| 090 ## - Yerel Tasnif No | |
| tasnif no | YL 3469 |
| Cutter no | S23 2024 |
| 100 1# - KİŞİ ADI | |
| Yazar Adı (Kişi adı) | Sadıq, Zainab Jega |
| 245 14 - ESER ADI BİLDİRİMİ | |
| Başlık | THE POTENTIAL WOUND HEALING ACTIVITY OF CHITOSAN-GUM ARABIC COMPLEX LOADED WITH CHAMOMILE AND HONEY / |
| Sorumluluk Bildirimi | ZAINAB JEGA SADIQ ; SUPERVISOR, ASST. PROF. DR. ALI ZAHER KAMEL AL-KALEEL |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024 |
| 300 ## - FİZİKSEL TANIMLAMA | |
| Sayfa, Cilt vb. | 55 sheets ; |
| Boyutları | 30 cm |
| Birlikteki Materyal | +1 CD ROM |
| 336 ## - CONTENT TYPE | |
| Source | rdacontent |
| Content type term | text |
| Content type code | txt |
| 337 ## - MEDIA TYPE | |
| Source | rdamedia |
| Media type term | unmediated |
| Media type code | n |
| 338 ## - CARRIER TYPE | |
| Source | rdacarrier |
| Carrier type term | volume |
| Carrier type code | nc |
| 502 ## - TEZ NOTU | |
| Tez Notu | Thesis (MSc) - Cyprus International University. Institute of Graduate Studies and Research Bioengineering |
| 520 ## - ÖZET NOTU | |
| Özet notu | The management of wounds creates a significant challenge in the healthcare sector. Any deviation in the natural healing process leads to impaired tissue regeneration, posing numerous problems. The use of chemical compounds to promote wound healing has been practiced for long time. However, the trajectory of modern medicine towards natural compounds necessitates finding new methods to enhance such compounds. The aim of this research is to synthesize a chitosan and gum Arabic polyelectrolyte complex loaded with chamomile and honey and explore its activities as a potential healing promoter.<br/>This study investigates the fabrication of a Chitosan -gum Arabic complex loaded with honey and chamomile as a potential wound healing promoter. Characterization analyses, including Zeta size, UV-Vis, and FTIR were carried out to determine the physicochemical properties of the complex. The antioxidant activity and cell migration activity of the synthesized nanoparticles were then analyzed to determine their potential as wound healing promoter. The synthesized nanoparticle exhibited the presence of alkyne, alkyl, hydroxyl, ester or ether and amines or amide groups similar to those in chitosan and gum Arabic, indicating their effective combination and formation of a complex. Phenol and alcohol groups were also present, likely attributed to the phenolic compounds in the honey and chamomile.<br/>The synthesized complex demonstrated enhanced radical scavenging activity compared to the herbal formulation and had a lower IC50 value than the extract and ascorbic acid, highlighting its increased efficacy at lower doses. There was also a significant increase in the rate of wound closure in the nanoparticles group compared to all other groups. The wound closure percentage increased with the concentration of nanoparticles. The synthesized Chitosan -gum Arabic complex has displayed favorable traits as a potential wound healing agent and warrants further to fully understand its chemical and biological properties. |
| 650 #0 - KONU BAŞLIĞI EK GİRİŞ - KONU TERİMİ | |
| Konusal terim veya coğrafi ad | Bioengineering |
| Alt başlık biçimi | Dissertations, Academic |
| 700 1# - EK GİRİŞ - KİŞİ ADI | |
| Yazar Adı (Kişi adı) | Al-Kaleel, Ali Zaher Kamel |
| İlişkili Terim | supervısor |
| 942 ## - EK GİRİŞ ÖGELERİ (KOHA) | |
| Sınıflama Kaynağı | Dewey Onlu Sınıflama Sistemi |
| Materyal Türü | Thesis |
| Geri Çekilme Durumu | Kayıp Durumu | Sınıflandırma Kaynağı | Kredi için değil | Koleksiyon Kodu | Kalıcı Konum | Mevcut Konum | Raf Yeri | Kayıt Tarih | Source of acquisition | Toplam Ödünçverme | Yer Numarası | Demirbaş Numarası | Son Görülme Tarihi | Kopya Bilgisi | Fatura Tarihi | Materyal Türü | Genel / Bağış Notu |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Onlu Sınıflama Sistemi | Tez Koleksiyonu | CIU LIBRARY | CIU LIBRARY | Depo | 16.10.2024 | Bağış | YL 3469 S23 2024 | T3916 | 16.10.2024 | C.1 | 16.10.2024 | Thesis | Bioengineering | ||||
| Dewey Onlu Sınıflama Sistemi | Tez Koleksiyonu | CIU LIBRARY | CIU LIBRARY | Görsel İşitsel | 16.10.2024 | Bağış | YL 3469 S23 2024 | CDT3916 | 16.10.2024 | C.1 | 16.10.2024 | Suppl. CD | Bioengineering |