Effect of royal jelly produced by Cyprus honeybees on breast cancer cells and clinically important bacteria Nneka Ogochukwu Onochie; Supervisor: Erkay Özgör
Dil: İngilizce Yayın ayrıntıları:Nicosia Cyprus International University 2019Tanım: VIII, 58 p. figure, table, color figure, graphic 30.5 cm CDİçerik türü:- text
- unmediated
- volume
Thesis
| Materyal türü | Geçerli Kütüphane | Koleksiyon | Yer Numarası | Durum | Notlar | İade tarihi | Barkod | Materyal Ayırtmaları | |
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Thesis
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CIU LIBRARY Tez Koleksiyonu | Tez Koleksiyonu | YL 1421 O56 2019 (Rafa gözat(Aşağıda açılır)) | Kullanılabilir | Bioengineering Department | T1564 |
Includes CD
Includes references (54-58 p.)
'ABSTRACT The aim of this study was to determine the content of cyprus royal jelly and investigate its effect on clinically important microrganisms and cancer (breast cancer cells MCF - 7 and MDA - MB-231). The Royal jelly used in this study showed antibacterial effect on four clinical bacterial strains. The gram positive organism named Bacilus subtilus showed more antibacteria effect at 100% while the gram negative organisms named klebsiela pnuemonia, psuedomonas auriginosa, escherichia coli showed less effect consecutively. RJ treatment did not show too much anti cancer effect on the cancer cell lines which was attributed to the organic contents present in royal jelly and the receptors ER,PR, in the cell line. However, MDA-MB231 showed 12.5 and 25% anti cancer effect at 24hr and 48hr respectively while for MCF-7 showed 75% and 12.5% anti cancer concentration effect at 24hr and 48hr respectively. Gas Chromotography Mass Spectroscopy performed showed significant peaks of the compounds present in royal jelly.. Royal Jelly is a potential tool for improvement in the quality of life and prognosis of patients treated with anti-cancer therapies. Keywords: Royal jelly, Anti-bacteria, Anti-cancer, Cell lines '