ANTICANCER EFFECT OF ETHANOLIC EXTRACT OF SOURSOP LEAVES AND SEEDS ON (MCF-7/MDA-MB-231) BREAST CANCER CELL LINES AND PROGESTERONE AND ESTROGEN RECEPTORS/ Abubakar Ahmed HUSSAINI; Supervisor: Erkay ÖZGÖR

Yazar: Katkıda bulunan(lar):Tanım: sheets IX, 73; charts, figures, tables, illustrations, 30.5 cm CDİçerik türü:
  • text
Ortam türü:
  • unmediated
Taşıyıcı türü:
  • volume
Konu(lar): Tez notu: Thesis (MSc.) - CYPRUS INTERNATIONAL UNIVERSITY INSTITUTE OF GRADUATE STUDIES AND RESEARCH Bioengineering Department Özet: ABSTRACT The aim of this research is to evaluate the phytochemicals screening from ethanol extract of annona muricata leave and seeds tested for in vitro cytotoxic activity against MCF-7/MDA-MB-231 cell lines progesterone and estrogen receptors and bacteria to provide the potent activity from plant. Studies of phytochemical which involved extraction using ethanol solvents. The phytochemicals screening such as test of secondary metabolites that the sample contained. The leave and seeds extract was assayed for cytotoxicity against MCF-7/MDA-MB-231 cell lines progesterone and estrogen receptors by using MTT assay. The studies of Phytochemicals results showed that the ethanolic extract of annona muricata leave and seeds contain saponins flavonoids and tannins. The activity of cytotoxic effect against MFC-7/MDA-MB-231 cell lines and progesterone and estrogen receptors showed the CD50 value less than 1μg/ml, that present as a very good activity. Keywords: Annona muricata, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, MDA-MB-231 cell lines.
Materyal türü: Thesis
Mevcut
Materyal türü Geçerli Kütüphane Koleksiyon Yer Numarası Durum Notlar İade tarihi Barkod Materyal Ayırtmaları
Thesis Thesis CIU LIBRARY Tez Koleksiyonu Tez Koleksiyonu YL 1786 H97 2020 (Rafa gözat(Aşağıda açılır)) Kullanılabilir Bioengineering Department T1992
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Includes CD

Thesis (MSc.) - CYPRUS INTERNATIONAL UNIVERSITY INSTITUTE OF GRADUATE STUDIES AND RESEARCH Bioengineering Department

Includes REFERENCES: sheets 63-68

ABSTRACT
The aim of this research is to evaluate the phytochemicals screening from ethanol extract of annona muricata leave and seeds tested for in vitro cytotoxic activity against MCF-7/MDA-MB-231 cell lines progesterone and estrogen receptors and bacteria to provide the potent activity from plant. Studies of phytochemical which involved extraction using ethanol solvents. The phytochemicals screening such as test of secondary metabolites that the sample contained. The leave and seeds extract was assayed for cytotoxicity against MCF-7/MDA-MB-231 cell lines progesterone and estrogen receptors by using MTT assay. The studies of Phytochemicals results showed that the ethanolic extract of annona muricata leave and seeds contain saponins flavonoids and tannins. The activity of cytotoxic effect against MFC-7/MDA-MB-231 cell lines and progesterone and estrogen receptors showed the CD50 value less than 1μg/ml, that present as a very good activity.
Keywords: Annona muricata, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, MDA-MB-231 cell lines.

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