INTRODUCTION Bioprocess Development: An Interdisciplinary Challenge 3 Introduction to Engineering Calculations 13 Presentations and Analysis of Data 45 MATERIAL AND ENERGY BALANCES Material Balance 87 Energy Balance 139 PHYSICAL PROCESS Fluid Flow 201 Mixing 225 Heat Transfer 333 Mass transfer 379 Unit Operations 445 REACTIONS AND REACTORS Homogenous Reactions 599 Heterogenous Reactions 705 Reactor Engineering 761 Appendices Index