000			03584nam a22003137a 4500
003			KOHA
005			20230707104043.0
008			230707d2023 cy ||||| |||| 00| 0 eng d
040			_aCY-NiCIU _beng _cCY-NiCIU _erda
041			_aeng
090			_aYL 2924 _bA34 2023
100	1		_aAdeji, Anthony Junior
245	1	0	_aSYNTHESIS AND CHARACTERIZATION OF ZINC OXIDE NANOPARTICLES VIA PLANT EXRTACT OF AGAVE AMERICANA / _cANTHONY JUNIOR ADEJI; SUPERVISOR: PROF. DR. HATICE ERKURT
264			_c2023
300			_aix, 59 sheets; _c31 cm. _eIncludes CD
336			_2rdacontent _atext _btxt
337			_2rdamedia _aunmediated _bn
338			_2rdacarrier _avolume _bnc
502			_aThesis (MSc) - Cyprus International University. Institute of Graduate Studies and Research Bioengineering Department
504			_aIncludes bibliography (sheets 52-59)
520			_aABSTRACT The fabrication of nanomaterials can be done using a variety of plant resources thanks to green technology, which also avoids the use of any processes that could be considered destructive. This research concentrates on an effective, simple, and eco friendly creation of ZnO nanoparticles using zinc sulfate heptahydrate and the bio components of dry agave powder extract (Agave americana). The characterization of the nanoparticles was done by using the analysis of Ultraviolet-Visible (UV-VIS) spectrophotometer, Fourier Transform Infrared (F.T-I.R), X-Ray Diffraction (X.R.D), and Scanning Electron Microscope (S.E.M). The size of the biosynthesized Zinc oxide nanoparticle was evaluated using the zeta size analyzer, which reveals that the biologically synthesized nanoparticle has an average size of 78nm. The presence of a peak between 271 and 289nm, which was observed via the uv-vis absorption is evidence that ZnONPs had been found. The S.E.M study shows a spherical form with a size range of 50 to 98nm while the X.R.D patterns indicated that the wurtzite structure is in the hexagonal phase. The existence of OH, C-H, C-O, and C-N stretching was demonstrated by the F.T-IR analysis. The use of a quantitative analysis of the aqueous solution of the leaf extract of agave americana enabled the detection of the presence of phytochemical compounds, and bioactive active compounds such as saponins, tannins, and flavonoids were present. According to the findings of the antioxidant activity, the aqueous plant extract and ZnONPs showed a scavenging value of 98% and 94% respectively, when the D.P.P.H assay was carried out. On the antibacterial experimentation, the bactericidal effect of both gram-positive (Bacillus subtilis) and gram-negative (Escherichia coli) bacteria were evaluated using the bio synthesized ZnONPs. B. subtilis and E.coli showed a zone of inhibition at 28mm and 5mm respectively. This research, confirmed the presence of pharmacologically active chemicals in the green synthesized ZnO nanoparticles which paves the door for their practical implementation in the therapeutic, treatment of industrial effluents and nanotechnology for drug delivery systems. Keywords; Agave americana, Antibacterial, Antioxidant, Characterization, Phytochemicals, Zinc Sulfate Heptahydrate, ZnONPs
650		0	_aAgaves _vDissertations, Academic
650		0	_aAntibacterial agents _vDissertations, Academic
650		0	_aAntibacterial agents _vDissertations, Academic
650		0	_aPhytochemicals _vDissertations, Academic
650		0	_aZinc sulfate _vDissertations, Academic
700	1		_aErkurt, Hatice _esupervisor
942			_2ddc _cTS
999			_c290538 _d290538