000 02562nam a22002777a 4500
003 KOHA
005 20241003155655.0
008 240730d2023 cy o|||| |||| 00| 0 eng d
040 _aCY-NiCIU
_beng
_cCY-NiCIU
_erda
041 _aeng
090 _aYL 3421
_bA38 2023
100 1 _aAbubakar, Rukayya
245 1 0 _aEVALUATION OF ANTIBACTARIAL AND ANTIOXIDANT ACTIVITIES OF SCHINUS MOLLE L. LEAF EXTRACT /
_cRUKAYYA ABUBAKAR ; SUPERVISOR DR. MARTHA ORENDU OCHE ATTAH
264 _c2023
300 _a39 sheets :
_bphotos ;
_c30 cm
_e+ 1 CD-ROM
336 _2rdacontent
_atext
_btxt
337 _2rdamedia
_aunmediated
_bn
338 _2rdacarrier
_avolume
_bnc
502 _aThesis (Msc) - Cyprus International University. Institute of Graduate Studies and Research Bioengineering Department
504 _aIncludes bibliography (sheets 33-39)
520 _aPlant based therapy has been used as an important component in traditional medicine. Plant also serves as inspiration for medicinal agents used in the defense against various pathogenic infections and diseases. Schinus molle is an ornamental tree growing in the Mediterranean area that has been used as topical antioxidant and antibacterial agent. This study aims at evaluating the antioxidant and antibacterial activity of schinus molle L. extract on escherichia coli and staphylococcus aureus as well as determining the bioactive components contained in the plant. The methods employed are phytochemical analysis, antioxidant assay, antibacterial screening and MIC test. The phytochemicals indicated presence of alkaloids, saponins, flavonoids, steroids, terpenoids and anthraquinone. Other phytochemicals such as glycosides were absent. The qualitative antioxidant assay revealed the presence of antioxidant activity through the formation of yellow spot against purple background on silica plate. The quantitative antioxidant assay also manifested DPPH scavenging activity through the IC50 value 2.250 and 1.465 for schinus molle L extract and ascorbic acid respectively. The antibacterial screening indicated a variable degree of sensitivity of the test isolates against the antibacterial agents used and the MIC determined the lowest concentration at which schinus molle L extract inhibited the growth of the test isolates. The value being 0.21 ± 1.92 for escherichia coli and 0.205+1.5 for staphylococcus aureus.
650 0 _aBioengineering
_vDissertations, Academic
700 1 _aAttah, Martha Orendu Oche
_esupervisor
942 _2ddc
_cTS
999 _c292684
_d292684