000 02405nam a22002657a 4500
003 KOHA
005 20250109101450.0
008 240927d2024 cy do||| |||| 00| 0 eng d
040 _aCY-NiCIU
_beng
_cCY-NiCIU
_erda
041 _aeng
090 _aYL 3514
_bM64 2024
100 1 _aMohamed, Deemah
245 1 0 _aCURCUMIN-LOADED ZINC OXIDE NANOPARTICLES FOR WOUND HEALING ON BREAST CANCER CELLS AS AN INTRO MODEL /
_cDEEMAH MOHAMED ; SUPERVISOR, ASST. PROF DR. ALI ZAHER KAMEL AL-KALEEL
264 _c2024
300 _a54 sheets ;
_c30 cm
_e+1 CD ROM
336 _2rdacontent
_atext
_btxt
337 _2rdamedia
_aunmediated
_bn
338 _2rdacarrier
_avolume
_bnc
502 _aThesis (MSc) - Cyprus International University. Institute of Graduate Studies and Research Bioengineering
520 _aWounds healing is a sophisticated biological process that involves numerous cellular and molecular activities. In recent years, nanotechnology has emerged as an appealing option for enhancing wound treatment methods. This work investigates the potential of curcumin-loaded zinc oxide nanoparticles (ZnO NPs) as an innovative therapeutic approach to enhance wound healing at the cellular level. The nanoparticles were synthesized using a green synthesis approach to ensure a safer method of production. Curcumin, an anti-inflammatory and antioxidant compound, was used to load the zinc oxide nanoparticles. The nanoparticles were characterized using Ultraviolet-Visible (UV-VIS) spectrophotometer, Fourier Transform Infrared (F.T-I.R) and X-Ray Diffraction (X.R.D). A zeta size analyzer was used to determine the size and charge of the biosynthesized zinc oxide nanoparticles, revealing that the biologically synthesized nanoparticle had an average size of nm. The incorporation of curcumin-loaded ZnO NPs with DMEM was investigated as a treatment for the wound healing assay to assess their potential in promoting wound closure. Curcumin and zinc oxide work together to enhance wound closure, making these nanoparticles a promising option for developing novel wound care therapies. Further research into the in-vivo effectiveness and safety of these nanoparticles will be critical to fully addressing their therapeutic potential.
650 0 _aBioengineering
_vDissertations, Academic
700 1 _aAl-kaleel, Ali Zaher Kamel
_esupervısor
942 _2ddc
_cTS
999 _c292972
_d292972